24.11.2013
CURRICULUM VITAE AND LIST OF PUBLICATIONS
1. Personal Details
Lazar, Isaac
Date and place of birth: June 12th, 1964, ISRAEL
Address (Office): Pediatric Intensive Care Unit, Soroka Medical center
2. Academic Education
Third degree MD
1995 University: Ben Gurion University of the Negev
Title of thesis The Evaluation of the Efficacy of Metered Dose Inhaler with Spacer and Mask in the Treatment of Asthma in Toddlers –Soroka University Medical Center – Beer Sheva, Israel – Awarded.
3. Professional Training
1995-1996 Intern, Rambam Medical Center, Technion Israel Institute of Technology, Haifa, Israel
1996-2001 Resident, Department of Pediatrics A, Rambam Medical Center, Technion Israel Institute of Technology, Haifa, Israel.
2001-2004 Postdoctoral Fellow, Section of Critical Care, CT Department of Pediatrics, Yale University School of Medicine, New Haven.
4. Board Certification
1996 Israel permanent MD
2001 General Pediatrics
2004 ECFMG permanent license (Step 1-3)
2006 Pediatric critical care (Isreali board)
5. Professional Licensing
Year of issue 1996 Medical License #28470
Year of issue 2001 Specialty License #18595
Year of issue 2007 Sub specialty License #23146
Year of issue 2004 CT (USA) Medical license #042719
6. Employment History
Intern, Rambam Medical Center, Technion Israel Institute of Technology, 1995 – 1996
Haifa, Israel
Resident, Department of Pediatrics Rambam Medical Center, Technion Israel 1996 – 2001
Institute of Technology, Haifa, Israel
Postdoctoral Fellow Department of Pediatrics Section of Critical Care 2001 –2004
Medicine Yale University School of Medicine, New Haven, CT
Senior Physician Department of Pediatrics Section of Critical Care Medicine 2001-2008
Yale University School of Medicine, New Haven, CT
Senior Physician Pediatric Intensive Care Unit Soroka Medical Center, Beer 2007-present
Sheva, Israel.
2013 – present Director – Pediatric Intensive Care Unit Soroka Medical Center, Beer Sheva,
Israel.
7. Academic Appointments
Instructor of Pediatrics Department of Pediatrics, Section of Critical Care, 7/2004- 6/2005
Medicine School of Medicine Yale University, New Haven CT.
Associate Research Scientist in Pediatrics Department of Pediatrics, 7/2005-8/2007
Section of Critical Care, Medicine School of Medicine Yale University,
New Haven CT.
9/2007 – 12/2008 Clinical Instructor Department of Pediatrics, Section of Critical Care,
Medicine School of Medicine Yale University, New Haven CT.
Clinical Instructor Pediatric intensive Care unit Faculty of Health sciences 2007-2011
Ben Gurion university of the Negev, Beer Sheva, Israel.
2011 – present Lecturer – Pediatric intensive Care unit Faculty of Health sciences Ben
Gurion university of the Negev, Beer Sheva, Israel.
8. Editor or Member of Editorial Board or Reviewer of Scientific or
Professional Journal
Respiratory Medicine Reviewer
9. Membership in Professional/Scientific Societies
Israel Medical Association 1995
Israel Pediatric Intensive Care Society 2001
Israel Pediatric Pulmonology Society 2008
Israel Intensive Care Society 2007
American Society of Critical Care 2002
American College of Chest Physicians 2003
European Society of Intensive Care Medicine 2007
European Society of Pediatric and Neonatal Intensive Care 2007
10. Educational Activities
Research students
Hiba Abu Caff Medical Student thesis – Blood Stream Infections in the PICU of Soroka 2008
medical center during the years 2000-2008 Ben Gurion university of the Negev, Beer
Sheva, Israel.
Yael Radinsky Medical Student thesis – Vascular catheter-related complications at 2009
the PICU, Soroka University Medical Center (2009-2010) Ben Gurion university of the
Negev, Beer Sheva, Israel.
Eti Gedz MA thesis – Effect of CDC based intervention plan for insertion and 2010
maintenance care of vascular catheters on catheter complication rate. Ben Gurion
university of the Negev, Beer Sheva, Israel.
Michal Leder MA thesis – Effect of structured informative interaction with the 2010
parents of children admitted to the pediatric intensive care unit, on the parent’s
anxiety level – a comparative study on different ethnic groups. Ben Gurion university
of the Negev, Beer Sheva, Israel.
Evyatar Hubra Pediatric resident thesis – Early detection of Central venous line 2011
related thrombosis – an ultrasonographic and biochemical approach Ben Gurion
university of the Negev, Beer Sheva, Israel.
Eitan Neeman Medical Student thesis – Change of Vascular catheter-related 2011
complications at the PICU, Soroka University Medical Center after implementing the
CDC based instructions. Ben Gurion University of the Negev, Beer Sheva, Israel.
11. Additional Functions
Ben-Gurion University
6 2009-present th year medical school committee member, Faculty of Health Sciences, Ben
Gurion University of the Negev, Beer Sheva, Israel.
2008-present Medical school candidates interviewer, Faculty of Health Sciences, Ben Gurion
University of the Negev, Beer Sheva, Israel.
Others
Israeli pediatric critical care boards exam member 2008-present
Clalit health services critical care and anesthesia equipment committee member 2010
Clalit health services pediatric critical care and neonatology equipment committee 2010
member
Member of special committee to assess the Liver transplant service in Schneider 2010
hospital – Assigned by Clalit health services CEO
PROSAFE member – promoting patient safety and quality improvement in critical 2010
care. a European project
Israeli pediatric critical care boards exam – Chairman 2011
12. Awards, Citations, Honors, Competitive Fellowships
Faculty of Health sciences, Ben Gurion university of the Negev, Bernard Zvical 1995
Research Award for Outstanding Research Project.
American Israeli fellowship foundation (APF), Pediatric critical care fellowship grant 1002
support.
13. Scientific Publications
Refereed articles in scientific journals
Lazar I, Weibel C, Ferguson D, Landry M, Kahn JS. Evidence that human .1
metapneumovirus does not contribute to the severity of respiratory syncytial virus
disease. Emerg Infect Dis. 10:1318-1320, 2004. (INFECTIOUS DISEASES IF 6.794, JR
3/52; CI 27).
Allon Canaan, Xiaofeng Yu, Carmen J. Booth, Jin Lian, Isaac Lazar, Serwa L. Gamfi, .2
Katrina Castille, Naohiko Kohya, Yasuhiro Nakayama, Yuan-Ching Liu, Elizabeth
Eynon,4 Richard Flavell, and Sherman M. Weissman. FAT10/Diubiquitin-Like Protein-
Deficient Mice Exhibit Minimal Phenotypic Differences. Mol Cell Biol. 2006
Jul;26(13):5180-9. (CELL BIOLOGY IF 6.057, JR 34/162; CI 15)
Lazar I, Canaan A, Weibel C, Kahn JS. Premature Stop Codons in the RSV G Gene .3
Identified in Viral Isolates from Girl with Severe Combined Immune Deficiency
Treated with IVIG. J Clin Virol. 2006 Nov;37(3):168-73. (VIROLOGY IF 3.124, JR 11/30)
Cavari Y, Sofer S, Rozovski U, Lazar I. Non invasive positive pressure ventilation in .4
infants with respiratory failure. Pediatr Pulmonol. 2012 Oct;47(10):1019-25
Levitz R, Wattier R, Phillips P, Solomon A, Lawler J, Lazar I, Weibel C, Kahn .5
JS.Induction of IL-6 and CCL5 (RANTES) in human respiratory epithelial (A549) cells
by clinical isolates of respiratory syncytial virus is strain specific. Virol J. 2012 Sep
10;9:190.
Isaac Lazar, Heba Abukaf, Shaul Sofer, Eugene Leibovitz. Bloodstream Infections at the Pediatric .6
Intensive Care Unit in Southern Israel (2000-2008): Epidemiological, Clinical and Microbiological
Aspects. Accepted for publication 2013. International journal of Infectious Diseases.
Case reports
Arnon Broides, Shaul Sofer, Isaac Lazar. Contact dermatitis with severe scalp swelling .1
and upper airway compromise due to black henna hair dye. Pediatric Emergency
Care 2011. (PEDIATRICS IF:0.916, JR 70/94)
Boris Knyazer, Jaime Levy, Eli Rosenberg, Prof’ Tova Lifshitz, Isaac Lazar*. Horner’s .2
syndrome in an infant with complicated pneumonia. IMAJ 2011 (GENERAL MEDICINE
IF 0.898 JR 81/133)
Landau D, Gurevich E, Kapelushnik J, Tamary H, Shelef I, Lazar I. Association .3
between childhood nephrotic syndrome and hemophagocytic lymphohistiocytosis.
Pediatr Nephrol. 2013 Dec;28(12):2389-92.
Cavari Y, Landau D, Sofer S, Leibson T, Lazar I.Organophosphate poisoning-induced .4
acute renal failure. Pediatr Emerg Care. 2013 May;29(5):646-7.
Cavari Y, Lazar I, Shelef I, Sofer S. Lethal brain edema, shock, and coagulopathy after .5
scorpion envenomation. Wilderness Environ Med. 2013 Mar;24(1):23-7
Cavari Y, Sofer S, Rozovski U, Lazar I. Non invasive positive pressure ventilation in .6
infants with respiratory failure – Response to letter. Pediatr Pulmonol. 2013
Jul;48(7):735-6.
Editorials and invited reviews and other reviews
Weiss R, Lazar I. The Need for Continuous Blood Glucose Monitoring in the Intensive .1
Care Unit. Journal of Diabetes Science and Technology, 2007;1(3):412-414.
Lazar I, Cavari Y, Rosenberg E, Knyazer B. Horner’s syndrome in patients admitted to .2
the paediatric intensive care unit: epidemiology, diagnosis and clinical practice.
Anaesth Intensive Care. 2013 Jan;41(1):20-3.
Books and chapters in books
Lazar I, Bogue C. Pediatric Critical Care Medicine – Basic Science and Clinical .1
Evidence. SECTION XI. The Immune System in Critical Illness and Injury. Chapter 123:
Infectious Disease-Associated Syndromes. 1511-1522. 2007
Lazar I, Bogue C. Pediatric Critical Care Medicine – Basic Science and Clinical .2
Evidence. 2nd edition. SECTION XI. The Immune System in Critical Illness and Injury.
Chapter 123: Infectious Disease-Associated Syndromes. In Press
Chapters in collective volumes – Conference proceedings
Lazar I, Knopf CF, Halberthal M, Gar-Joseph G. Asialotransferrin as a biochemical .1
marker for subarachnoid-pleural fistula diagnosis. Pediatric Research. Volume: 55
Issue: 4 Pages: 66A-67A Part: Part 2 Suppl. S Supplement: Part 2 Suppl. S
Meeting Abstract: 376 Published: APR 2004
Lazar I, Weibel C, Ferguson D, Landry M, Kahn JS. Evidence that human .2
metapneumovirus does not contribute to the severity of respiratory syncytial virus
disease. Pediatric Research. Volume: 55 Issue: 4 Pages: 59A-59A Part: Part 2 Suppl.
S Supplement: Part 2 Suppl. S Meeting Abstract: 331 Published: APR 2004
I Lazar, Y Cavari and S Sofer. Noninvasive positive pressure ventilation in infants with .3
respiratory failure. 29th International Symposium on Intensive Care and Emergency
Medicine. Brussels, Belgium. 24–27 March 2009. Critical Care 2009, 13(Suppl 1):P8
14. Lecture and Presentations at National and International Meetings
Lazar I, Weibel C, Ferguson D, Landry M, Kahn JS. Evidence that human .1
metapneumovirus does not contribute to the severity of respiratory syncytial virus
disease. Society of Pediatric Research meeting. San Francisco. May 2004.
Lazar I, Kahn JS RSV – things I learned from the virus Israeli Pediatric Pulmonology yearly .2
meeting Israel 2008
Lazar I, Cavari Y, Sofer S Noninvasive positive pressure ventilation in infants with .3
respiratory failure Israeli Pediatric Pulmonology yearly meeting Israel 2009
Lazar I, Benifla M Medical and surgical approach to severe complicated head trauma in .4
children Grand rounds Soroka medical center 2009
Isaac Lazar. Pediatric Critical Care 2011. 2011 GIVITI International meeting. Pesaro, ITALY .5
Isaac Lazar. CREACTIVE and Children. CREACTIVE study kick off meeting\ GIVITI .6
International meeting. 2013 Pesaro, ITALY.
15. Competitive and Non-competitive Research Grants
The health services planning and research funds – Clalit health services 2011
Lazar I (PI), Sofer S, Leibowitz E, Gedz E, Grinshpon L. Effect of CDC based
intervention plan for insertion and maintenance care of vascular catheters on
.)₪03290(catheter complication rate, 1 year, $13,500
2012 Effect of structured informative interaction with the parents of children admitted to
the pediatric intensive care unit, on the parent’s anxiety level – a comparative study
on different ethnic groups. 1 year , $13,500
2013 CREACTIVE – Prospective longitudinal data collection and Comparative
Effectiveness Research (CER) for traumatic brain injury (TBI). 5 years. 5.600.000
Euro.
16. Present Academic Activities
Research in progress
PROSAFE project – Promoting patient safety and quality improvement in critical .1
care. a European project involving 8 partners from Cyprus, Germany, Hungary, Italy,
Poland, Slovenia, United Kingdom and an external collaboration with Brazil. I serve
as the Israeli administrator and coordinator center with plans to expand the project
to other PICU in Israel.
Central Line project: Ongoing longitudinal prospective study (started nov 2009) on .2
central venous and arterial line related complications in cildren admitted to the
PICU.
Hematological and biochemical markers for early detection of central venous line .3
related venous thrombosis.
Parental anxiety project- Factors contriburing to parental anxiety of children .4
admitted to the PICU. How does early nurse based intervention approach effect the
anxiety level of parents from different ethnic groups (native Jewish Israeli, Beduin,
previously USSR born) – collaboration with pediatric psychiatry trauma service.
CREACTIVE – National coordinator, International coordinator of Pediatric Sub-study .5
and steering committee member. CREACTIVE is an International multicenter study
on acute and long term outcome of patients with Traumatic Brain Injury admitted to
the intensive Care Unit.
